In addition to recommendations for control of the traditional risk factors, spreading information about the potential adverse effect of opium use, which has only recently been associated with higher risk of CAD, may be necessary.
A prominent finding of this study is confirming opium use was associated with a much younger age of CAD onset, even after adjusting for all other risk factors. The major results of this study (lower age of CAD diagnosis in men, lower age of diagnosis associated with most risk factors, and lower prevalence of serum lipids over time) were expected. Of particular interest, opium consumption was associated with 2.2 year earlier age of CAD diagnosis. All lipid profile components (total cholesterol, low-density lipoprotein cholesterol, triglycerides, and high-density lipoprotein cholesterol) decreased over time. Increasing trend was seen in body-mass index, hypertension prevalence, diabetes mellitus. Mean age at diagnosis had an overall increasing trend during the study period. Men were younger at diagnosis than women, with a mean age of 60.1 in men and 63.2 in women ( p < 0.001), and had fewer risk factors at the time of diagnosis. Resultsįrom January 2005 to December 2015, data for 90,094 patients were included in this analysis. The prevalence and 11-year trends of conventional CAD risk factors were analyzed by sex and age, and their adjusted effects on the age of CAD diagnosis were calculated. Adult patients who had obstructive (> 50% stenosis) CAD were included in the study.
Cad risk factors timi serial#
We conducted a registry-based, serial cross-sectional study using the coronary angiography data bank of the Tehran Heart Center. In this study, we aimed to determine prevalence and trends of CAD risk factors in patients with documented CAD and to determine their effects on the age of CAD diagnosis. 64 (24):e139-e228.Coronary artery disease (CAD) is a universal public health challenge, more prominently so in the low- and middle-income countries. 2014 AHA/ACC Guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Amsterdam EA, Wenger NK, Brindis RG, et al.
What is the Yield of Testing for Coronary Artery Disease after an Emergency Department Attendance with Chest Pain?. Screening Characteristics of TIMI Score in Predicting Acute Coronary Syndrome Outcome a Diagnostic Accuracy Study.
Chest Pain Risk Scores Can Reduce Emergent Cardiac Imaging Test Needs With Low Major Adverse Cardiac Events Occurrence in an Emergency Department Observation Unit. Wang H, Watson K, Robinson RD, Domanski KH, Umejiego J, Hamblin L, et al. Early versus late percutaneous revascularization in patients hospitalized with non ST-segment elevation myocardial infarction: The atherosclerosis risk in communities surveillance study. 284(7):835-42.Īrora S, Matsushita K, Qamar A, Stacey RB, Caughey MC.
The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making. Antman EM, Cohen M, Bernink PJ, McCabe CH, Horacek T, Papuchis G.
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